I would love to hear of others' experience with the drug flecainide. I began taking it about two months ago and was given a prescription for 100 mg twice a day to supress ventricular tachycardias that began for no apparent reason or trigger. It was almost 15 months to the day of having a pacemaker/ICD implanted for reasons that were later determined to be false (I have posted my story here before).
Flecainide does supress the VTs but brings along a portfolio of side effects that are almost unbearable -- difficulty breating, dizziness, headaches. But no VTs. I was STUNNED to find out upon my own research that the doctors never should have given me a blanket prescription. They shold have given me a loading dose and then a maintenanc dose. I reduced my dosage from 100 mg to 50 and then to 25 mg twice a day -- didn't ask my docs because I was so angry.
The side effects went away and the VTs remained supressed with the lower dose. But the effects are coming back. Here's what I think. Becasue the half-life (the time it takes for half the dose to leave your body) of flecainide is between 12 and 27 hours (huge), if you stay on even a small course, your body eventually becomes saturated and reaches a toxic level. That is why I felt fine initially with the lower dose. Now it's reached that toxic level again.
I shifted my dosing to 25 mg every 17 hours instead of 12, hoping to overcome that long half-life. Again, I feel fine and hope it lasts. These are adjustments I'm making on my own with success. My doctors have little to offer. And becaue flecainide isn't a cure but rather a supressor, if I continue having NO VTs, I've acheived the best this drug is intended to do for me.